Characterisation of anticryptococcal Fc-1 toxin of Filobasidium capsuligenum

نویسنده

  • Andrea Keszthelyi
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Anti-cryptococcal Killer Toxin

s: Keszthelyi A Characterisation of anticryptococcal FC-1 toxin of Filobasidium capsuligenum, Acta Biologica Szegediensis Volume 50(3-4):155, 2006 Posters: 35th Annual Conference on Yeasts, 2007, Smolenice, Slovakia, Poster: Andrea Keszthelyi, Zoltan Farkas, Zsuzsanna Hamari, Ilona Pfeiffer, Csaba Vágvölgyi, Judit Kucsera Comparison of killer toxin producing and toxin non-producing Filobasidium...

متن کامل

Cloning and expression of tetanus toxin C fragment (Fc) in prokaryotic vector for constructing recombinant protein based vaccine for tetanus

Tetanus is a disease caused by tetanus toxin, a potent inhibitor for the release of inhibitory neurotransmitter in the central nervous system that causes spastic paralysis. Fragment C (52 kD) of this toxin is responsible for binding to the neuronal membrane. For this reason, and also its non toxigenic and immunogenic nature, this fragment might be ideal for new vaccine development. Presently, w...

متن کامل

Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design

CMG2-Fc is a fusion protein composed of the extracellular domain of capillary morphogenesis protein 2 (CMG2) and the Fc region of human immunoglobulin G; CMG2-Fc neutralizes anthrax toxin and offers protection against Bacillus anthracis challenge. To enhance the efficacy of CMG2-Fc against anthrax toxin, we attempted to engineer a CMG2-Fc with an improved affinity for PA. Using the automatic de...

متن کامل

Protein Expression and Purification

1046-5928/$ see front matter 2009 Elsevier Inc. A doi:10.1016/j.pep.2009.09.016 * Corresponding author. Fax: +1 215 503 6795. E-mail address: [email protected] (M 1 Two authors contributed equally. 2 Abbreviations used: PA, protective antigen; ATR/C capillary morphogenesis protein 2; VWA, the von Wil fragment of human immunoglobulin. Mass vaccination against anthrax with existing vac...

متن کامل

Antitumor activities of TEM8-Fc: an engineered antibody-like molecule targeting tumor endothelial marker 8.

Tumor endothelial marker 8 (TEM8) was discovered as a cell membrane protein that is predominantly expressed in tumor endothelium and identified as a receptor for anthrax toxin. We developed an antibody-like molecule that consists of the protective antigen (PA)-binding domain of human TEM8 linked to the Fc portion of human immunoglobulin G1 (TEM8-Fc). This engineered protein bound to PA in a div...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006